Researching With Purpose

Depression affects over 300 million people worldwide. This is an increase of more than 18% from 2005 to 2015. Depression is a disease of epidemic proportions. Among those seeking treatment, approximately 60% still experience symptoms of depression even when receiving traditional care.

The need for better solutions is clear.

Usona embraces the challenge of finding a better way forward. We are a non‑profit, medical research organization looking beyond the traditional treatments for depression. Our aim is to enable and support research toward the goal of an FDA registration for psilocybin as an approved medicine.

Research is formalized curiosity.

- Zora Neale Hurston

MD Minute

Usona’s Director of Clinical and Translational Research, Chuck Raison, MD, discusses: the latest in depression research; depression, psilocybin, and clinical trials; and what clinical trial participation is like in three videos.

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The Latest in Depression Research


Depression is a health crisis of epic proportions. Current treatments don’t work for everyone, and some people choose not to take treatments because of side effects or withdrawal symptoms. Learn more about current depression treatments as well as the importance of finding new and novel treatments for the disease.

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Depression, Psilocybin, & Clinical Trials

Interest in psychedelics as a treatment for depression is not new. Trials were conducted in the 1950s and 1960s. Many were promising but lacked the rigor and control of today’s studies. Today’s studies use improved scientific designs to better determine if psychedelics are useful for the treatment of conditions like depression.

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What Clinical Trial Participation is Like

Clinical trial participation is very different from visiting your regular doctor. Your regular doctor may prescribe an already approved drug for a condition. As a clinical trial participant, you’re an active part of the drug approval process. Learn more about this and how participation helps science move forward.

Explore Our Trials

  Explore Our Trials

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Learn more before exploring our trials.